hrp0097rfc5.4 | Diabetes and insulin 1 | ESPE2023

Effect of probiotic on glycemic control in children with type 1 diabetes: A randomized controlled trial

Elshebrawy Hadeer , El-Hawary Amany , El-Husseiny Ahmed , Laymoun Wafaa

Background: Studies in animal models and humans with type 1 diabetes mellitus (T1DM) have shown that probiotic supplementation leads to decreased proinflammatory cytokines (responsible for damaging β-cells of the pancreas), improved gut barrier function, and induction of immune tolerance.Objective: To study the effect of supplementation of probiotics in children with T1DM on glycemic control, insulin total daily dos...

hrp0097p1-432 | Diabetes and Insulin | ESPE2023

Prevalence of sleep disorders in children and adolescents with type 1 diabetes and its relation to glycemic control: A single center study

Fawzy Hesham , Elziny Magdy , Aboelenin Hadil , Laymoun Wafaa

Background: Poor sleep quality has been linked to insulin resistance and impaired glucose metabolism, but little is known about sleep and type 1 diabetes (T1D). People with T1D experience higher rates of sleep disturbances than people without diabetes, and these disturbances have negative implications on glycemic control, as well as psychosocial and cognitive outcomes.Objective: To study the prevalence of sleep disorders...